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β‐1,3/1,6‐glucans and Immunity: State of the Art and Future Directions

Elena De Marco Castro, Philip C Calder, Helen M Roche First published: 29 March 2020, https://doi.org/10.1002/mnfr.201901071   Abstract: The innate immune system responds in a rapid and non‐specific manner against immunologic threats; inflammation is part of this response. This is followed by a slower but targeted and specific response termed the adaptive or acquired immune Continue reading…

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial

Biofortis, Mérieux NutriSciences, Addison, IL, USA Mah E, Kaden VN, Kelley KM, Liska DJ (2018) Journal of Dietary Supplements. Abstract: Objective: In this double-blind, randomized, placebo-controlled parallel study, we examined the effect of dairy-based beverages (250 mL/day) containing 250 mg of dispersible baker’s yeast b-glucan (Wellmune) compared to a macronutrient- and calorie-matched control on upper Continue reading…

Oral Supplementation with Baker’s Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise

Applied Physiology Laboratory, University of North Texas McFarlin BK, Venable AS, Carpenter KC, Henning AL, Ogenstad S. (2017) Frontiers in Physiology 8:786. Abstract: Objective: Exercise and physical labor in extreme environmental conditions causes transient decreases in immune cell and cytokine concentrations, likely increasing the susceptibility to opportunistic infection. Baker’s yeast beta glucan (BYBG) has been Continue reading…

A β-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohn’s Disease and Control Subjects

University of Örebro, Sweden Ganda Mall J-P, Casado-Bedmar M, Winberg ME, Brummer RJ, Schoultz I, Keita ÅV. Inflammatory Bowel Diseases 24:166–78. Abstract: Background: Administration of β-glucan has shown immune-enhancing effects. Our aim was to investigate whether β-glucan could attenuate mast cell (MC)-induced hyperpermeability in follicle-associated epithelium (FAE) and villus epithelium (VE) of patients with Crohn’s Continue reading…

Baker’s Yeast Beta Glucan Supplementation Increases Monocytes and Cytokines Post-Exercise: Implications of Infection Risk?

Carpenter KC, Breslin WL, Davidson T, Adams A, McFarlin BK. (2013) British Journal of Nutrition 109:478-486. Abstract: Strenuous aerobic exercise is known to weaken the immune system, and while many nutritional supplements have been proposed to boost post-exercise immunity, few are known to be effective. The purpose of the present study was to evaluate whether Continue reading…

Yeast-Derived Beta 1,3/1,6 Glucan, Upper Respiratory Tract Infection and Innate Immunity in Older Adults

University of SouthHampton  Fuller R, Moore MV, Lewith G, Stuart BL, Ormiston RV, Fisk HL, Noakes PS, Calder PC. (2017)   Nutrition 39-40:30-35 Abstract:  Objective: This study aimed to test whether yeast-derived beta 1,3/1,6 glucan can prevent the occurrence or reduce the severity of upper respiratory tract infection (URTI) and modulate innate immune responses during winter Continue reading…

Baker’s Yeast Beta-Glucan Decreases Episodes of Common Childhood Illness In 1 to 4 Year Old Children during Cold Season in China.

H&J CRO International, Inc Meng F. (2016)  Journal of Nutrition & Food Science 2016; 6:518. Abstract: Introduction: Infections, especially upper respiratory tract infections (URTI) are common in early childhood, which creates a large economic burden on both the healthcare system and individual family. There are many foods and dietary supplement ingredients intended to improve children’s Continue reading…

Cow’s Milk-Based Beverage Consumption in 1- to 4-Year-Olds and Allergic Manifestations: an RCT

Developmental and Behavioral Pediatric Department, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China Clinical Research, Department of Medical Affairs, Mead Johnson Nutrition, Evansville, Indiana Pontes MV, Ribeiro TCM, Ribeiro H, de Mattos AP, Almeida IR, Leal VM, Cabral GN, Stolz S, Zhuang W, Scalabrin DMF. (2016) Nutrition Journal 15:19-28. Abstract:  Background: Continue reading…

Baker’s Yeast Beta Glucan Supplementation Increases Salivary IgA and Decreases Cold/Flu Symptomatic Days After Intense Exercise

Applied Physiology Laboratory, College of Education, University of North Texas, Denton, Texas, USA Department of Kinesiology, Health Promotion, and Recreation, University of Minnesota, Minneapolis, MN, USA Laboratory of Integrated Physiology, University of Houston, Houston, Texas, USA  McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. (2013) Journal of Dietary Supplements 10:171-183.   Abstract: Strenuous exercise, such as Continue reading…

Baker’s Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women

Talbott SM, Talbott JA. (2012) Journal of the American College of Nutrition 31:295-300 Abstract: Objective: Several studies have shown a baker’s yeast beta-1,3/1,6-D-glucan, extracted from Saccharomyces cerevisiae, is effective in reducing the incidence of cold and flu symptoms. This study evaluated the effect of a specific beta-glucan supplement (Wellmune) on upper respiratory tract symptoms and psychological well-being Continue reading…

ß-Glucan Supplementation, Allergy Symptoms and Quality of Life in Self-Described Ragweed Allergy Sufferers

Talbott SM, Talbott JA, Talbott TL, Dingler E. (2013) ß Food Science & Nutrition 1:90-101. Abstract:  This randomized, placebo-controlled, double-blind study compared the effects of daily supplementation for 4 weeks with 250 mg Wellmune WGP® β-1,3/1,6-Glucan (WGP) with placebo 250 mg/day (rice flour) on physical and psychological health attributes of self-described “moderate” ragweed allergy sufferers. Continue reading…

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