Research Behind Wellmune®.
Unlike other yeast beta glucans, Wellmune® is the only ingredient supported by over a dozen published, peer-reviewed clinical studies. Research validates Wellmune’s unique ability to help strengthen general immune health across all ages.
Wellmune’s clinical research has demonstrated consistent results across a broad range of people, including:
Peer-reviewed published studies.
Research is at the heart of what we do. Learn about our research by viewing the published studies below.
Boutros JA, Magee AS, Cox D. ‘Comparison of structural differences between yeast β-glucan sourced from different strains of saccharomyces cerevisiae and processed using proprietary manufacturing processes’. Food Chemistry. 2021 Jul 28; 367:130708.
De Marco Castro E, Calder PC, Roche HM. (2020) b-1,3/1,6 glucans and Immunity: State of the Art and Future Directions. Molecular Nutrition and Food Research, https://doi.org/10.1002/mnfr.201901071.
Eunice Mah, Valerie N. Kaden, Kathleen M. Kelley & DeAnn J. Liska (2018): Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. Journal of Dietary Supplements, DOI:10.1080/19390211.2018.1495676.
McFarlin BK, Venable AS, Carpenter KC, Henning AL, Ogenstad S. (2017) Oral Supplementation with Baker’s Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise. Frontiers in Physiology 8:786.
Fuller R, Moore MV, Lewith G, Stuart BL, Ormiston RV, Fisk HL, Noakes PS, Calder PC. (2017) Yeast-Derived Beta 1,3/1,6 Glucan, Upper Respiratory Tract Infection and Innate Immunity in Older Adults. Nutrition 39-40:30-35.
Meng F. (2016) Baker’s Yeast Beta-Glucan Decreases Episodes of Common Childhood Illness In 1 to 4-Year-Old Children during Cold Season in China. Journal of Nutrition & Food Sciences 6:518.
Pontes MV, Ribeiro TCM, Ribeiro H, de Mattos AP, Almeida IR, Leal VM, Cabral GN, Stolz S, Zhuang W, Scalabrin DMF. (2016) Cow’s Milk-Based Beverage Consumption in 1- to 4-Year-Olds and Allergic Manifestations: an RCT. Nutrition Journal 15:19-28.
Li F, Jin X, Liu B, Zhuang W, Scalabrin D. (2014) Follow-up Formula Consumption in 3- to 4-Year-Olds and Respiratory Infections: An RCT. Pediatrics 133:e1533-40.
McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. (2013) Baker’s Yeast Beta Glucan Supplementation Increases Salivary IgA and Decreases Cold/Flu Symptomatic Days After Intense Exercise. Journal of Dietary Supplements 10:171-183.
Carpenter KC, Breslin WL, Davidson T, Adams A, McFarlin BK. (2013) Baker’s Yeast Beta-Glucan Supplementation Increases Monocytes and Cytokines Post-Exercise: Implications of Infection Risk? British Journal of Nutrition 109:478-486.
Talbott SM, Talbott JA, Talbott TL, Dingler E. (2013) ß-Glucan Supplementation, Allergy Symptoms and Quality of Life in Self-Described Ragweed Allergy Sufferers. Food Science & Nutrition 1:90-101.
Fuller R, Butt H, Noakes PS, Kenyon J, Yam TS, Calder PC. (2012) Influence of Yeast-Derived 1,3/1,6 Glucopolysaccharide on Circulating Cytokines and Chemokines with Respect to Upper Respiratory Tract Infections. Nutrition 28:665-669.
Talbott SM, Talbott JA. (2012) Baker’s Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women. Journal of the American College of Nutrition 31:295-300.
Talbott S, Talbott J. (2010) Beta 1,3/1,6 Glucan Decreases Upper Respiratory Tract Infection Symptoms and Improves Psychological Well-Being in Moderate to Highly-Stressed Subjects. Agro FOOD Industry Hi-Tech 21:21-24.
Talbott S, Talbott J. (2009) Effect of Beta 1,3/1,6 Glucan on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. Journal of Sports Science and Medicine 8:509-515.
Feldman S, Schwartz HI, Kalman DS, Mayers A, Kohrman HM, Clemens R, Krieger DR. (2009) Randomized Phase II Clinical Trials of Wellmune® for Immune Support During Cold and Flu Season. Journal of Applied Research 9:30-42.
Harger-Domitrovich SG, Domitrovich JW, Ruby BC. (2008) Effects of an Immunomodulating Supplement on Upper Respiratory Tract Infection Symptoms in Wildland Firefighters. Medicine & Science in Sports & Exercise 40:S353.
Have questions or want to learn more about our research? Our R&D team can help.